Correlation Between Endometrial Thickness By Ultrasonography and Histopathology in Abnormal Uterine Bleeding
Keywords:
Abnormal uterine bleeding, endometrium, histopathology, ultrasonography
Abstract
Background : Abnormal uterine bleeding (AUB) is the most common presenting complaint of patients in Gynaecology Outpatient department. Early diagnosis of endometrial hyperplasia through ultrasongraphic measurement of endometrial thickness and definite diagnosis by histopathologic examination will help the clinicians to give appropriate treatment to the patients. The objective of this study was to correlate the histopathology findings in abnormal uterine bleeding with endometrial thickness by ultrasonography. Methods : This was a prospective study done from Nov 2016 to June 2018.A total of 382 cases of AUB presenting above 40 years of age were included. Endometrial thickness was measured by ultrasonography. Histopathological findings were studied and compared with the endometrial thickness. Statistical analysis were done using chi square test. Results : A total of 382 cases were analysed. Maximum number of cases were from peri menopausal age group (68.32%). Majority of the cases were due to non organic causes(85.34%). 46.86% of patients had endometrial thickness of 5-10mm followed by endometrial thickness of 11-15mm in 39.01%. Disordered proliferative endometrium was the most common pattern (38.34%) in our study followed by secretory endometrium (35.58%) and menstrual endometrium (18.71%). These findings were found to be statistically significant. Conclusion : A thorough histopathological work up and clinical correlation is mandatory in cases of abnormal uterine bleeding above 40 years to find out organic lesions. Careful screening can detect precursor lesions like endometrial hyperplasia and early cases of endometrial carcinoma which has excellent prognosis and it will help in further management.References
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of Medical Sciences. July 2014, 1(2), 75–79.
2. Singh M, Sachan R, Yadav A. Significance of endometrial thickness on transvaginal sonography in heavy menstrual bleeding. J Curr Res Sci Med 2019;5:28-32.
3. Ibrahim SA, Ibrahim MA. Study the Accuracy of Transvaginal Ultrasound Combined with Endometrial Office Biopsy (Pipelle) as a Predictor of Final Pathology in Patients with Abnormal Uterine Bleeding. J Clin Obstet Gynecol Infertil. 2019; 3(1): 1038
4. Agrawal S, Mathur A, Vaishnav K.Histopathological study of endometrium
in abnormal uterine bleeding in women of all age groups in Western Rajasthan
(400 cases).International Journal of Basic and Applied Medical Sciences.2014;4(3):15-18.
5. Pillai SS. Sonographic and histopathological correlation and evaluation of
endometrium in perimenopausal women with abnormal uterine bleeding Int J
Reprod Contracept Obstet Gynecol. 2014 Mar;3(1):113-117.
6. Wankhade A, Vagha S, Shukla S, Bhake A, Laishram S, Agrawal D, et al. To correlate histopathological changes and transvaginal sonography findings in the endometrium of patients with abnormal uterine bleeding. J Datta Meghe Inst Med Sci Univ2019;14:11-5.
7. Shajitha S., Sangeereni M and Mallika A.The Study Of Endometrial
Thickness by Transvaginal USG With Its Histopathology Correlation In
Abnormal Uterine Bleeding International Journal Of Current Medical And
Pharmaceutical Research, October, 2017; Vol. 3(10):2487-2490,
8. Dr. S. GeethaLakshmi,“Ultrasonographic Measurement of Endometrial Thickness and Histopathological Diagnosis of Endometrial Hyperplasia in Abnormal Uterine Bleeding -A Correlative Study” IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), vol. 17, no. 10, 2018, pp 14-19.
9. Chaudhari L, Satia MN. To study the correlation between endometrial thickness on transvaginal sonography and endometrial histopathology in women with
postmenopausal bleeding. Int J Reprod Contracept Obstet Gynecol 2016;5:1309-15.
10. Singh P, Dwivedi P, Mendiratta S.Correlation of endometrial thickness with the histopathological pattern of endometrium in postmenopausal bleeding. J Obstet Gynaecol India.2016 Feb;66(1)42-6.
11. Shrestha P, Shrestha S,Mahato V.Endometrial study by Ultrasonography and its correlation with histopathology in abnormal uterine bleeding. Asian Journal of Medical
Sciences | Mar-Apr 2018.Vol 9 ( 2):31-5.
12. Sur D, Chakravorty R (2016) Correlation of Endometrial Thickness and
Histopathology in Women with Abnormal Uterine Bleeding. Reprod Syst Sex
Disord ;2016 5(4): 192.
13. Das B.P, Deka N, Saikia J. Evaluation of Endometrium with Sonographic and
Histopathological Correlation in Perimenopausal Women with Dysfunctional
Uterine Bleeding.International Journal of Science and Research, October 2017; Vol
6(10):1774-7.
14. Getpook C., Wattanakumtornkul S. Endometrial thickness screening in premenopausal women with abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Research. 2006;32:588-92.
15. Parihar M, Parihar A. Peri- and postmenopausal uterine bleeding transvaginal ultrasound with hysterosonography and diagnostic correlation with hysteroscopy. Donald School Journal of Ultrasound in Obstetrics & Gynecology. 2012;5(4):343-52.
of Medical Sciences. July 2014, 1(2), 75–79.
2. Singh M, Sachan R, Yadav A. Significance of endometrial thickness on transvaginal sonography in heavy menstrual bleeding. J Curr Res Sci Med 2019;5:28-32.
3. Ibrahim SA, Ibrahim MA. Study the Accuracy of Transvaginal Ultrasound Combined with Endometrial Office Biopsy (Pipelle) as a Predictor of Final Pathology in Patients with Abnormal Uterine Bleeding. J Clin Obstet Gynecol Infertil. 2019; 3(1): 1038
4. Agrawal S, Mathur A, Vaishnav K.Histopathological study of endometrium
in abnormal uterine bleeding in women of all age groups in Western Rajasthan
(400 cases).International Journal of Basic and Applied Medical Sciences.2014;4(3):15-18.
5. Pillai SS. Sonographic and histopathological correlation and evaluation of
endometrium in perimenopausal women with abnormal uterine bleeding Int J
Reprod Contracept Obstet Gynecol. 2014 Mar;3(1):113-117.
6. Wankhade A, Vagha S, Shukla S, Bhake A, Laishram S, Agrawal D, et al. To correlate histopathological changes and transvaginal sonography findings in the endometrium of patients with abnormal uterine bleeding. J Datta Meghe Inst Med Sci Univ2019;14:11-5.
7. Shajitha S., Sangeereni M and Mallika A.The Study Of Endometrial
Thickness by Transvaginal USG With Its Histopathology Correlation In
Abnormal Uterine Bleeding International Journal Of Current Medical And
Pharmaceutical Research, October, 2017; Vol. 3(10):2487-2490,
8. Dr. S. GeethaLakshmi,“Ultrasonographic Measurement of Endometrial Thickness and Histopathological Diagnosis of Endometrial Hyperplasia in Abnormal Uterine Bleeding -A Correlative Study” IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), vol. 17, no. 10, 2018, pp 14-19.
9. Chaudhari L, Satia MN. To study the correlation between endometrial thickness on transvaginal sonography and endometrial histopathology in women with
postmenopausal bleeding. Int J Reprod Contracept Obstet Gynecol 2016;5:1309-15.
10. Singh P, Dwivedi P, Mendiratta S.Correlation of endometrial thickness with the histopathological pattern of endometrium in postmenopausal bleeding. J Obstet Gynaecol India.2016 Feb;66(1)42-6.
11. Shrestha P, Shrestha S,Mahato V.Endometrial study by Ultrasonography and its correlation with histopathology in abnormal uterine bleeding. Asian Journal of Medical
Sciences | Mar-Apr 2018.Vol 9 ( 2):31-5.
12. Sur D, Chakravorty R (2016) Correlation of Endometrial Thickness and
Histopathology in Women with Abnormal Uterine Bleeding. Reprod Syst Sex
Disord ;2016 5(4): 192.
13. Das B.P, Deka N, Saikia J. Evaluation of Endometrium with Sonographic and
Histopathological Correlation in Perimenopausal Women with Dysfunctional
Uterine Bleeding.International Journal of Science and Research, October 2017; Vol
6(10):1774-7.
14. Getpook C., Wattanakumtornkul S. Endometrial thickness screening in premenopausal women with abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Research. 2006;32:588-92.
15. Parihar M, Parihar A. Peri- and postmenopausal uterine bleeding transvaginal ultrasound with hysterosonography and diagnostic correlation with hysteroscopy. Donald School Journal of Ultrasound in Obstetrics & Gynecology. 2012;5(4):343-52.
Published
2020-04-03
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