A Rare Case Presentation of HbE/ β Thalassemia

  • Anu Singh Department of Pathology, ABVIMS & Dr RML Hospital, New Delhi
  • Vijay Kumar Department of Pathology, ABVIMS & Dr RML Hospital, New Delhi
  • Meetu Singh Department of Pathology, ABVIMS & Dr RML Hospital, New Delhi
  • Priya Sahu Department of Pathology, ABVIMS & Dr RML Hospital, New Delhi
  • Garima Baweja Specialist, department of pathology
  • Sadhna Marwah Department of Pathology, ABVIMS & Dr RML Hospital, New Delhi
Keywords: Thalassemia, heterozygous pedigree analysis


HbE/β thalassemia (HbE/β thal) genotype accounts for approximately one half of severe β thalassemia cases worldwide. The disorder shows marked clinical variability ranging from mild asymptomatic anemia to life threatening disease. Here, we report a case of a 2-year-old boy from Bihar presenting with severe haemolytic jaundice. Complete haematological profile and Haemoglobin High Performance Liquid Chromatography (Hb HPLC) using Biorad version was done of the patient along with the family was done to arrive at the diagnosis of this rare hemoglobinopathy.


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Case Report