Invasive Solid Mucinous Papillary Carcinoma Breast with Neuroendocrine Differentiation: A Case Report with Immunohistochemical Study

  • Jyoti Mishra Department of Pathology, School of Medical Sciences and Research, Sharda Hospital, Greater Noida, Uttar Pradesh.
  • Srijan Srivastav Department of Pathology Lady Hardinge Medical College, New Delhi
  • Natasha Singh Department of Pathology, School of Medical Sciences and Research, Sharda Hospital, Greater Noida, Uttar Pradesh
  • Varun Prasad Department of Anaesthesia, School of Medical Sciences and Research, Sharda Hospital, Greater Noida, Uttar Pradesh
Keywords: Invasive Solid Papillary carcinoma, neuroendocrine, mucin, immunohistochemistry


Solid papillary carcinoma of the breast (SPCB) is a distinctive form of papillary carcinoma that tends to occur in older women and usually has a favorable prognosis. We describe an invasive solid papillary carcinoma with extracellular and intracellular mucin and neuroendocrine differentiation in a 60-year old female. The cytological features have been also been highlighted with an insight on differentials that were helpful in its correct identification preoperatively.


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