A Rare Case Report of Serous Cystadenoma with Coexisting Sclerosing Stromal Tumor of Ovary

  • Lachit Kalita Department of Pathology, Barpeta Cancer Centre, Assam Cancer Care, Barpeta , Assam.
  • Abhijit Kalita Department of Pathology, Barpeta Cancer Centre, Assam Cancer Care, Barpeta , Assam.
  • Munmun Harlalka Department of Pathology, Barpeta Cancer Centre, Assam Cancer Care, Barpeta , Assam.
Keywords: Ovarian epithelial neoplasms, serous cystadenoma, sclerosing stromal tumor


Various forms of collision tumors have been reported in literature before. Ovarian tumors also exhibit different histological components at times. The epithelial neoplasm of ovary in coexistence with sertoli leydig cell tumor, granulosa cell tumor, cystic teratoma and stromal tumor with minor sex cord elements are known to exist. However, literature related to association of serous neoplasm of ovary with sclerosing stromal tumor is not known. We report a case of serous cystadenoma with coexisting sclerosing stromal tumor in a 31-year-old lady which is probably one of the first case reports of such a combination till date.


Sujithra S, Rani U, Sundaram S, Sundaram S, Rajendiran S, Susruthan M. Ovarian Collision Tumors. J South Asian Feder Obst Gynae 2020;12(5):331–334

Shaw JA, Dabbs DJ, Geisinger KR. Sclerosing stromal tumor of the ovary: an ultrastructural and immunohistochemical analysis with histogenetic considerations. Ultrastructural Pathology. 1992 Jan 1;16(3):363-77.

Chalvardjian A, Scully RE. Sclerosing stromal tumors of the ovary. Cancer. 1973 Mar;31(3):664-70.

Hsu C, Ma L, Mak L. Sclerosing stromal tumor of the ovary: case report and review of the literature. International journal of gynecological pathology. 1983 May 1;2(2):192-200.

Quinn MA, Oster AO, Fortune D, Hudson B. Sclerosing stromal tumour of the ovary case report with endocrine studies. BJOG: An International Journal of Obstetrics & Gynaecology. 1981 May;88(5):555-8.

Tsukamoto N, Nakamura M, Ishikawa H. Sclerosing stromal tumor of the ovary. Gynecologic Oncology. 1976 Sep 1;4(3):335-9.

Tiltman AJ. Sclerosing stromal tumor of the ovary. Int J Gynecol Pathol. 1985;4:362-69.

Seidman JD, Mehrotra A. Benign ovarian serous tumors: a re-evaluation and proposed reclassification of serous “cystadenomas” and “cystadenofibromas”. Gynecologic oncology. 2005 Feb 1;96(2):395-401.

Russel, P. (1994) Surface epithelial stromal-tumors of the ovary. In: Kurman, R.J., Ed., Blaustein’s Pathology of the Female Genital Tract, 4th Edition, Spinger-Verlag, New York, 724.

Jayalakshmy PS, Poothiode U, Krishna G, Jayalakshmy PL. Ovarian fibroma with serous cystadenoma—an unusual combination: a case report. Case reports in Obstetrics and Gynecology. 2012 Jan 1;2012.

Yang SW, Cho MY, Jung SH, Lee KG, Cha DS, Kim KR. Mucinous cystadenoma coexisting with stromal tumor with minor sex-cord elements of the ovary: a case report. Journal of Korean medical science. 2001 Apr 1;16(2):237-40.

Bachhav AA. Serous cystadenoma with co-existing stromal tumor with sex-cord stromal elements: An extremely rare tumor. Open Journal of Obstetrics and Gynecology. 2014 Feb 21;2014.

Singh AK, Singh M. Collision tumours of ovary: a very rare case series. Journal of clinical and diagnostic research: JCDR. 2014 Nov;8(11):FD14.

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