Peritoneal De-differentiated Liposarcoma: A Rare Case Report

  • Gauri Vinod Hardas Pathology, KIMS-Kingsway Hospitals, Nagpur, Maharashtra
  • Lalit Lad Pathology, KIMS-Kingsway Hospitals, Nagpur, Maharashtra
  • Harshwardhan Bora Pathology, KIMS-Kingsway Hospitals, Nagpur, Maharashtra
  • Saurabh Prasad Pathology, KIMS-Kingsway Hospitals, Nagpur, Maharashtra
Keywords: De-differentiated liposarcoma, Immunohistochemistry


Peritoneal de-differentiated liposarcoma is a rare malignancy with a poor prognosis. Our patient, 67 years/Male presented with complaints of constipation & distension of abdomen for one month. Initially based on histology, diagnosis of Gastrointestinal Stromal Tumor (GIST) was thought. On PET scan, he had multiple peritoneal deposits & serosal deposits along recto-sigmoid colon and ileal loop which on immunohistochemistry (IHC) proved to be de-differentiated liposarcoma. The patient was given chemotherapy. Patient responded well to treatment. Such peritoneal tumors pose a challenge to the pathologist as only morphology is not of much help & IHC becomes necessity.


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Case Report