An evaluation of histopathological findings of skin biopsies in various skin disorders

  • Sanjeev Narang Department of Pathology, Index Medical College, Indore
  • Ravi Jain Department of Pathology, MGM Medical College, Indore
Keywords: Skin Biopsy, Histopathology, Leprosy,


Background - Skin conditions are among the most common health problems in India. Skin biopsy is most common diagnostic technique for diagnosing skin disease. The interpretation of a skin biopsy requires clinicopathological correlation.Methods: The present study was undertaken in the Department of Pathology, M.G.M Medical College and M.Y. Hospital, Indore (M.P) to determine the incidence and age-sex distribution of various skin diseases, to study the various histopathological changes encountered in the course of the study and to establish clinic pathological correlation. A total number of 262 biopsies retrieved from the archives during the period of January 2007 to June 2008 along with skin biopsies sent for histopathological evaluation during June 2008 – June 2010 were included in the study. On the basis of histopathological classification the skin disorders are divided into eight groups.Result: Maximum number of cases belonged to group V disorders i.e. disorders showing perivascular, diffuse and granulomatous infiltrates of the reticular dermis 65(24.8 %), followed by group VI disorders that is tumors and cysts of the dermis 28(10.7 %). Out of 262 skin biopsies which came for Histopathological evaluation, 137 (52.3 %) cases were given definite diagnosis by microscopic examination of slides. Amongst 216 cases, clinico-histopathological correlation was seen in 95(44 %) cases. Highest number of cases 68(25.95 %) were observed in the age group of 21-30 years, with majority of the cases were male 149(56.9 %) while 113(43.1 %) cases were female.Conclusion: Leprosy is still most prevalent, thereby emphasizing stronger measures to control it.

Author Biographies

Sanjeev Narang, Department of Pathology, Index Medical College, Indore
Professor, Department of Pathology, Index Medical College, Indore
Ravi Jain, Department of Pathology, MGM Medical College, Indore
Assistant ProfessorDepartment of PathologyMGM Medical College, Indore


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Original Article