Non-Immune Hydrops Foetalis due to Congenital Toxoplasmosis: a rare case report with review of literature.

  • Mallikarjun Adiveppa Pattanashetti Assistant Professor , Department of Pathology, S.Nijalingappa Medical College , Bagalkot
  • Vijayalaxmi V Suranagi Professor, Department of Pathology, Jawaharlal Nehru Medical College, Belagavi
  • Hema B Bannur Professor, Department of Pathology, Jawaharlal Nehru Medical College, Belagavi
Keywords: Non-Immune Hydrops Foetalis, toxoplasmosis, hypoplastic lungs


Non-Immune Hydrops Foetalis (NIHF) implies an excess of total body water which manifests as extracellular accumulation of fluid in serous cavities and soft tissues of foetus without any detectable circulating antibody against RBC antigen. Toxoplasmosis is an important congenitally acquired infectious cause of NIHF.Mother had complaints of fever, reduced foetal movements, USG showed hydrops foetalis and she tested positive for Toxoplasma IgG antibodies. On autopsy, foetus had generalised subcutaneous oedema, bilateral hypoplastic lungs  with pleural effusion and oedema of brain with ventriculomegaly suggestive of  hydrocephalus. We report a rare case of NIHF due to congenital toxoplasmosis with bilateral hypoplastic lungs, with emphasis on epidemiology and prevention of toxoplasmosis. DOI: 10.21276/APALM.1077


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Case Report