Comparison Of Diagnostic Accuracy Of BIRADS Score With Pathologic Findings In Breast Lumps
Keywords:
BIRADS, Fine-needle aspiration cytology, Histopathology, Breast Lump.
Abstract
Background: Breast lump is one of the commonest complaints with which patients present in breast clinics. As approximately 10% of breast masses ultimately lead to a diagnosis of breast cancer, it is important for women with a breast lump to receive appropriate evaluation. A confident diagnosis can be made in 95% of the cases through a combination of clinical examination, imaging and fine needle aspiration cytology. Histopathology is the gold standard for diagnosis.Methods: This is a prospective study conducted in the Department of Pathology, K.V.G Medical College, Sullia on 50 patients who presented with clinically palpable breast lump. Patients were subjected to sonomammography and Breast Imaging Reporting and Data System (BIRADS) scoring followed by FNAC and histopathological examination. Sensitivity, specificity, accuracy, positive and negative predictive values of sonomammogram in relation to the BIRADS score and FNAC taking histopathology as the gold standard was calculated.Result: FNAC had significantly higher sensitivity, specificity ,positive and negative predictive values and accuracy compared to sonographical diagnosis using BIRADS Score. Conclusion: FNAC could be considered as the first method to evaluate breast lesions, recognized by means of imaging techniques.DOI: 10.21276/APALM.1124References
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Role of Mammography Combined with Ultrasonography in Evaluation of Breast Lump. American Journal of Public Health Research. 2015;3(5A):95-8.
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Mammography, Sonomammography In Correlation With Fine Needle
Aspiration Of Breast Lumps. Int J Biol Med Res. 2014;5(3):4370-6.
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8. Yalavarthi S, Tanikella R, Prabhala S, Tallam US. Histopathological and cytological correlation of tumors of breast. Medical Journal of Dr. D.Y. Patil University. 2014;7 (3):326-31.
9. Taori K, Dhakate S, Rathod J, Hatgaonkar A, Disawal A, Wavare P et al. Evaluation of Breast Masses Using Mammography and Sonography as First Line Investigations. Open Journal of Medical Imaging. 2013;3:40-49.doi.org/10.4236/ojmi.2013.31006.
10. Heinig J, Witteler R, Schmitz R, Kiesel L, Steinhard J. Accuracy of classification of breast ultrasound findings based on criteria used for BI-RADS. Ultrasound Obstet Gynecol. 2008;32:573–78.
11. TakhellambamYS, Lourembam SS, Sapam OS, Kshetrimayum RS, Thoujam BS, Khan T. Comparison of Ultrasonography and Fine Needle Aspiration Cytology in the Diagnosis of Malignant Breast Lesions. Journal of Clinical and Diagnostic Research. 2013;7(12):2847-50.
12. Shumaila SM, Tayyiba A, Safdar AM. Mammographic – Sonographic co-relation in the diagnosis of breast lump. Biomedica. 2008;24:147-51.
13. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid Breast Nodules: Use of Ultrasonography to Distinguish between Benign and Malignant Lesions. Radiology. 1995;196(1):123-34.
14. Emine D, Suzana M, Halit Y, Arben K. Comparative accuracy of mammography and ultrasound in women with breast symptoms according to age and breast density. Bosn J Basic Med Sci. 2009;9:131-6.
15. Vala MT, Goswami A, Suri SK. Comparative study of cytological and histopathological finding in breast lesion. IOSR Journal of Dental and Medical Sciences. 2014;13(7):05-07.
16. Qin Z, NieShigui, Yuhua C, Limei Z. Fine Needle Aspiration Cytology of Breast Lesions: Analysis of 323 Cases. The Chinese-German Journal of Clinical Oncology. 2004;3(3):172-4.
17. Tiwari M. Role of FNAC in diagnosis of breast lumps. Kathmandu University Medical Journal. 2007;5:215-17.
18. Bukhari MH, Arshad M, Jamal S, Niazi S, Bashir S, Bakhshi IM. Use of fine-needle aspiration in the evaluation of breast lumps. Patholog Res Int. 2011;doi:10.4061/2011/689521
19. Velu ARK, Srinivasamurthy BC, Rani J. Cytological evaluation of benign breast lesions with histopathological correlation. Indian Journal of Pathology and Oncology. 2016;3(1):7-10.
20. Moschetta M, Telegrafo M, Carluccio DA, Jablonska JP, Rella L, Serio G et al. Comparison between fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in the diagnosis of breast lesions. G Chir. 2014;35(7/8):171-6.
2. Lalchan S, Thapa M, Sharma P, Shrestha S, Subash K, Pathak M et al.
Role of Mammography Combined with Ultrasonography in Evaluation of Breast Lump. American Journal of Public Health Research. 2015;3(5A):95-8.
3. Chairat R, Puttisri A, Pamarapa A, Samintharapanya S, Tawichasri C, Patumanod J. Are Both Ultrasonography and Mammography Necessary for Cancer Investigation of Breast Lumps in Resource-Limited Countries? ISRN Oncology. 2013;Article ID 257942, doi:10.1155/2013/257942.
4. Arsalan F, Subhan A, Rasul S, Jalali U, Yousuf M, Mehmood Z et al. Sensitivity and specificity of BI-RADS scoring system in carcinoma of breast. Journal of Surgery Pakistan. 2010;15(1):38-43.
5. Phurailatpam J, Sakalecha A, Prasad CS, Kumar BN, Hegde P. Evaluation Of
Mammography, Sonomammography In Correlation With Fine Needle
Aspiration Of Breast Lumps. Int J Biol Med Res. 2014;5(3):4370-6.
6. Quershi S A, Rehman K, Muhammad D, Khan M I, Jaffra H. Validity of Mammogram according to Bi-RADS Scoring In Relation with Histopathology among Females Presenting with Clinically Palpable Breast lump or Nipple discharge. Ann Pak Inst Med Sci. 2014;10(3):150-4.
7. Daramola AO, Odubanjo MO, Obiajulu FJ, Ikeri NZ. Correlation between Fine needle aspiration cytology and histology for palpable breast masses in a Nigerian tertiary health institution. International Journal of breast Cancer. 2015;Article ID 742573, doi:10.1155/2015/742573.
8. Yalavarthi S, Tanikella R, Prabhala S, Tallam US. Histopathological and cytological correlation of tumors of breast. Medical Journal of Dr. D.Y. Patil University. 2014;7 (3):326-31.
9. Taori K, Dhakate S, Rathod J, Hatgaonkar A, Disawal A, Wavare P et al. Evaluation of Breast Masses Using Mammography and Sonography as First Line Investigations. Open Journal of Medical Imaging. 2013;3:40-49.doi.org/10.4236/ojmi.2013.31006.
10. Heinig J, Witteler R, Schmitz R, Kiesel L, Steinhard J. Accuracy of classification of breast ultrasound findings based on criteria used for BI-RADS. Ultrasound Obstet Gynecol. 2008;32:573–78.
11. TakhellambamYS, Lourembam SS, Sapam OS, Kshetrimayum RS, Thoujam BS, Khan T. Comparison of Ultrasonography and Fine Needle Aspiration Cytology in the Diagnosis of Malignant Breast Lesions. Journal of Clinical and Diagnostic Research. 2013;7(12):2847-50.
12. Shumaila SM, Tayyiba A, Safdar AM. Mammographic – Sonographic co-relation in the diagnosis of breast lump. Biomedica. 2008;24:147-51.
13. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid Breast Nodules: Use of Ultrasonography to Distinguish between Benign and Malignant Lesions. Radiology. 1995;196(1):123-34.
14. Emine D, Suzana M, Halit Y, Arben K. Comparative accuracy of mammography and ultrasound in women with breast symptoms according to age and breast density. Bosn J Basic Med Sci. 2009;9:131-6.
15. Vala MT, Goswami A, Suri SK. Comparative study of cytological and histopathological finding in breast lesion. IOSR Journal of Dental and Medical Sciences. 2014;13(7):05-07.
16. Qin Z, NieShigui, Yuhua C, Limei Z. Fine Needle Aspiration Cytology of Breast Lesions: Analysis of 323 Cases. The Chinese-German Journal of Clinical Oncology. 2004;3(3):172-4.
17. Tiwari M. Role of FNAC in diagnosis of breast lumps. Kathmandu University Medical Journal. 2007;5:215-17.
18. Bukhari MH, Arshad M, Jamal S, Niazi S, Bashir S, Bakhshi IM. Use of fine-needle aspiration in the evaluation of breast lumps. Patholog Res Int. 2011;doi:10.4061/2011/689521
19. Velu ARK, Srinivasamurthy BC, Rani J. Cytological evaluation of benign breast lesions with histopathological correlation. Indian Journal of Pathology and Oncology. 2016;3(1):7-10.
20. Moschetta M, Telegrafo M, Carluccio DA, Jablonska JP, Rella L, Serio G et al. Comparison between fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in the diagnosis of breast lesions. G Chir. 2014;35(7/8):171-6.
Published
2017-06-04
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