Leiomyomatous hamartoma of the pyloric antrum: A Case Report

  • Geetanjali Gupta Govind Ballabh Pant Institute of Post-Graduate Medical Education and Research
  • Pallavi Agrawal
  • Hirdaya Nag
  • Puja Sakhuja
Keywords: Gastric antrum, Hamartoma, Leiomyoma


Leiomyomatous hamartomas are extremely rare lesions with very few cases being reported in the lungs and the oral cavity. There has been no published report of gastric leiomyomatous hamartoma till date. We present a case of leiomyomyomatous hamartoma in the pyloric antrum clinically mimicking a gastrointestinal stromal tumour. A 49-year old female presented with abdominal pain since 3 months. Endoscopy and Contrast-enhanced CT showed a large, well-defined, submucosal lesion in the antropyloric region, causing mild luminal compromise. In our case, distal gastrectomy (Bilroth 1) was done.  Histopathological examination revealed a lesion comprising of proliferating connective tissue with smooth muscle fascicles dispersed in loose fibrous stroma, nerves and multiple small vessels. Immunophenotyping with smooth-muscle actin and desmin supported the diagnosis. We report this rare case and suggest the inclusion of leiomyomatous hamartoma in the differential diagnosis of gastric lesions with smooth muscle as a dominant component.

Author Biography

Geetanjali Gupta, Govind Ballabh Pant Institute of Post-Graduate Medical Education and Research
Department of Pathology


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Case Report