An Insight Into Pituitary Fossa Lesions: A single institutional experience
Keywords:
Sellar, Pituitary, Adenoma, Craniopharyngioma, Sqaush Cytology
Abstract
Introduction: The complex placement of the sellar region and the various native tissues provide a fertile ground for the development of spectrum of non-neoplastic and neoplastic lesions in this area.Methods: The prospective study of two years in a tertiary care hospital was conducted. A total of 67 specimens of sellar and parasellar region were received from the neurosurgery department for intraoperative as well as histopathological diagnosis. Squash cytology was utilised for rapid intraoperative consultation.Results: Pituitary adenomas were the most common tumours followed by craniopharyngiomas.Conclusion: Multidisciplinary approach of radiology, neurosurgery and pathology helps in arriving at the right conclusion and diagnosis in central nervous system lesions.References
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9) Saeger W, Lüdecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S. Pathohistological classification of pituitary tumours: 10 years of experience with the German pituitary tumour registry. European J Endocrinol. 2007;156: 203-216.
10) Valassi E, Biller BM, Klibanski A, Swearingen B. Clinical features of nonpituitarysellar lesions in a large surgical series. ClinEndocrinol (Oxf). 2010;73:798-807.
11) Cho HJ, Kim H, Kwak YJ, et al. Clinicopathologic Analysis of Pituitary Adenoma - A Single Institute Experience. J Korean Med Sci 2014;29:405-410.
12) Rishi A, Sharma MC, Sarkar C, Jain D, Singh M, Mahapatra AK, Mehta VS, Das TK. A clinicopathological and immunohistochemical study of clinically non-functioning pituitary adenomas: A single institutional experience. Neurology India. 2010;58:418-423.
13) Matshana, John K. Analysis of pituitary tumours: retrospective study at Chris Hani Baragwanath and Charlotte Maxeke Johannesburg academic hospitals, 1999-2008. [Available from: http://hdl.handle.net/10539/8798]
14) Plata AO, Tena-Suck ML, Neri IP, Bojórquez DR, Fernández A. Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study, Pituitary Adenomas, VafaRahimi-Movaghar (Ed.). 2012. ISBN: 978-953-51-0041-6, InTech, Available from: http://www.intechopen.com/books/pituitary-adenomas/pituitary-adenomas-clinico-pathologicalimmunohistochemical-and-ultrastructural-study
15) Mindermann T, Wilson CB. Age related and gender related occurrence of pituitary adenomas. ClinEndocrinol (Oxf). 1994;41:359-64.
16) Daly AF, Jaffrain-Rea ML, Ciccarelli A, Socin HV et al. Clinical Characterization of Familial Isolated Pituitary Adenomas. J Clin Endocrinol Metab. 2006;91:3316-3323.
17) De Mello PA, Naves LA, Neto AP, et al. Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas. ArqNeuropsiquiatr. 2013;71:307-312.
18) Reddy R, Cudlip S, Byrne JV, Karavitaki N, Wass JA. Can we ever stop imaging in surgically treated and radiotherapy–naïve patients with non- functioning pituitary adenoma? Eur J Endocrinol. 2011; 165:739-44
2) Kleinschmidt BK, De Masters. Pituitary gland. In: Juan Rosai, editor. Rosai and Ackerman's Surgical Pathology. 10th ed. Edinburgh. Mosby Elsevier; 2012. 2441-2461.
3) Lloyd RV, Kovacs K, Young Jr WF, et al. Tumours of the Pituitary gland. In: De Lellis RA, Lloyd RV, Heitz PU, Eng C, editors. World Health Organization Classification of Tumours. Pathology and genetics of Tumours of Endocrine Organs. Lyon, France. IARC; 2004. 10-13.
4) Scheithauer BW, Kovacs K, Horvath E, et al. Pituitary carcinoma. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, eds. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Endocrine Organs. Lyon, France. IARC Press; 2004. 36-39.
5) Rushing EJ , Giangaspero F, Paulus W, et al. Craniopharyngioma. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, eds. WHO Classification of Tumours of the Central Nervous System. Lyon, France. IARC Press; 2007. 238-240.
6) Adamson TE, Wiestler OD, Kleihues P, Yasargil MG. Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J Neurosurg. 1990;73:12-17.
7) Burger PC, Scheithauer BW, Vogel FS. Region of the sella turcica. In: Surgical pathology of the Nervous system and its coverings. 4th ed. New York. Churchill Livingstone; 2001. 437-490.
8) Scheithauer BW. The Pituitary and Sellar Region. In: Mills SE, Carter D, Greenson JK, Reuter VE, Stoler MH, editors. Sternberg’s Diagnostic Surgical Pathology. 5th ed. Philadelphia. Lippincott Williams & Wilkins; 2010. 460-488.
9) Saeger W, Lüdecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S. Pathohistological classification of pituitary tumours: 10 years of experience with the German pituitary tumour registry. European J Endocrinol. 2007;156: 203-216.
10) Valassi E, Biller BM, Klibanski A, Swearingen B. Clinical features of nonpituitarysellar lesions in a large surgical series. ClinEndocrinol (Oxf). 2010;73:798-807.
11) Cho HJ, Kim H, Kwak YJ, et al. Clinicopathologic Analysis of Pituitary Adenoma - A Single Institute Experience. J Korean Med Sci 2014;29:405-410.
12) Rishi A, Sharma MC, Sarkar C, Jain D, Singh M, Mahapatra AK, Mehta VS, Das TK. A clinicopathological and immunohistochemical study of clinically non-functioning pituitary adenomas: A single institutional experience. Neurology India. 2010;58:418-423.
13) Matshana, John K. Analysis of pituitary tumours: retrospective study at Chris Hani Baragwanath and Charlotte Maxeke Johannesburg academic hospitals, 1999-2008. [Available from: http://hdl.handle.net/10539/8798]
14) Plata AO, Tena-Suck ML, Neri IP, Bojórquez DR, Fernández A. Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study, Pituitary Adenomas, VafaRahimi-Movaghar (Ed.). 2012. ISBN: 978-953-51-0041-6, InTech, Available from: http://www.intechopen.com/books/pituitary-adenomas/pituitary-adenomas-clinico-pathologicalimmunohistochemical-and-ultrastructural-study
15) Mindermann T, Wilson CB. Age related and gender related occurrence of pituitary adenomas. ClinEndocrinol (Oxf). 1994;41:359-64.
16) Daly AF, Jaffrain-Rea ML, Ciccarelli A, Socin HV et al. Clinical Characterization of Familial Isolated Pituitary Adenomas. J Clin Endocrinol Metab. 2006;91:3316-3323.
17) De Mello PA, Naves LA, Neto AP, et al. Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas. ArqNeuropsiquiatr. 2013;71:307-312.
18) Reddy R, Cudlip S, Byrne JV, Karavitaki N, Wass JA. Can we ever stop imaging in surgically treated and radiotherapy–naïve patients with non- functioning pituitary adenoma? Eur J Endocrinol. 2011; 165:739-44
Published
2016-10-11
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