Histopathology of gastrointestinal tract malignancies: A two year retrospective study.
Keywords:
Gastrointestinal malignancy, Adenocarcinoma, Squamous cell carcinoma
Abstract
Background: Incidence of gastrointestinal malignancies is gradually increasing. The aim of the study is to determine age, sex and relative frequencies of various.Methods: Gastrointestinal malignancies diagnosed between January 2014 to December 2015 in MGM Medical College and Hospital, Aurangabad. In this descriptive retrospective study, total of 180 cases of gastrointestinal malignancies were diagnosed in our institution. Demographic and histopathological data were retrieved from the case files and histopath request forms. The slides were microscopically reviewed to confirm the diagnosis.Result: The mean age of the patients was 56 years (SD =13). Peak incidence was in between 40-60years. Male to female ratio of 1.5:1 was recorded. The common GI malignancies were esophageal(50.8%) followed by large intestine (50%).Other anatomic sites affected are stomach(36.6%), perianal region(9.1%) and small intestine(3.3%).Microscopically, adenocarcinoma was the commonest malignancy(67%)followed by squamous cell carcinoma(28%).Conclusion: Gastrointestinal tract malignancies are one of most common cancers in our country. . The incidence has been increasing due to life style changes and these cancers are usually diagnosed late when the disease has already invaded the lamina propria and musculature, because in early stages, the patient usually complains of trivial and nonspecific symptoms. Hence a new look to epidemiological studies in gastric cancer is necessary along with necessary focus on lifestyle modification. DOI: 10.21276/APALM.1246References
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2.Shahid Jamal,Nadira Mamoom et al.Analysis of Gastrointestinal malignancies at Armed forces institute of Pathology,Raalpindi,Pakistan.Asia Pacific Journal of Cancer prevention,2005;6:497-500.
3.Patel Madakini M,Gamit Bhavna,Patel Prashant R.Analysis of Gastrointestinal Malignancy:A five years study.National Journal of Community Medicine.July-Sept2012,Vol3,issue3;555-557.
4.Claudia Pauna,Elena Lazar.Colorectal Carcinoma-Epidemiological and Histopathological aspect.Cercetari Experimentale and Medico-Chirurgicale.2006;anuIXIII:53-56.
5.Amma Khurshed,Rashida ahmed et al.Primary Gastrointestinal malignancies in childhood and Adolescence-an asian Perspective.Asian Pacific Journal of Cancer prevention.2007;8:613-617.
6.Fatima Biade Abdulkareem,Emmanuel Kunle Abudu et al.Colorectal carcinoma in Lagos and sagamu,Southwest Nigeria:A histopathological review.World Journal of Gastroenterology 2008November 14;14(42):6531-6535.
7.Nasima Chandra,A.R Khan et al.Histopathology of gastric cancer in Kashmir-A five year retrospective Analysis.JK SCIENCE.January-March2007;9(1):21-23.
8.Jijo V.Cherian,Ramalingam Sivaraman et al.Carcinoma of the Esophagus in Tamil Nadu(South India):16 years trend from Tertiary Center.J Gastrointestin Liver Dis September 2007;16(3):245-249.
9.Helena Kollarova,Lucie Machova et al.Epidemiology of Esophageal Cancer-An overview Article.Biomed Pap Med Fac Univ Palacky Olomouc Czech Rpub.200;151(1
):17-28
10.Mieittinen M,Sobin LH,Lasota J (2005)Gastrointestinal stromal tumors of stomach:A clinicopathologic,immunohistochemical and molecular genetic study of 1765 cases with long term follow up.Am J Surg Pathol 29:52-68
11.Berman J,O`Leary TJ(2001) Gastrointestinal stromal tumor workshop.Hum Pathol 32:578-582.
12 Ioannis Hatzaras,MD;J Alexander Palety,MD;et al.Small Bowel Tumors Epidemiologic and Clinical Characteristics of 1060 Cases from the Connecticut Tumor Registry.(Reprinted)ARCH SURG. Mar 2007;14:229-235.
13.D. Max Parkin,MD,Paola pisani,Ph D et al.Global Cancer Statistics.Cancer Journal for clinicians.January/February 1999;49(1):33-63.
14 Rajesh Sing Laishram,Nisa Kalho,Rachel Shimray et al.Histopathological Evaluation of Colorectal Carcinoma Sttus in Manipur,India.International Journal of Pathology.;2010;8(1):5-8.
14. Hossen Froutan, Pishbijari, A retrospective study of gastrointestinal cancers in Theran, Medical Journal of the Islamic Republic of Iran ,Volume 20, November 2006.
Published
2017-08-31
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