Soft Tissue Chondromas: A case series of 6 cases with review
Soft tissue chondroma is extraskeletal benign cartilagenous soft tissue tumor rare to their skeletal counterpart enchondromas. They manifest characteristic radiological and histological features with consistent cytological features. Although several histologic studies of soft tissue chondromas have been published, correlative studies of cytologic, radiologic and corresponding histologic features are limited. To better define the triad of cytological, radiological and histological features of various Soft tissue chondroma, we reviewed the radiological and corresponding cytohistologic material of six tumors. The radiological finding consists of a well defined soft tissue mass, partly calcified not attached to underlying bone. Classical cytological patterns were found to be small clusters of benign appearing chondrocytes along with chondromyxoid fragment, with a impression of soft tissue chondroma. Post operatively all six cases show characteristic histologic features consisting of adult type hyaline cartilage with mild atypia in chondocytes in one and inflammation in other tumor. The cyto-histologic features along with radiologic feature constitute definitive triad in diagnosing soft tissue chondromas.
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Nayler S, Heim s. Soft tissue chondroma. In: Fletcher CD, Unni KK, Mertens F (Eds). Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; 2006. pp. 180-1.
Khedhaier A, Maalla R, Ennouri K, Regaya N. Soft tissues chondromas of the hand : A report of five cases. Acta Orthop. Belg. 2007:73;458-61.
Haktanır NT, Demir Y, Haktanır A, Aktepe F, Sancaktar N. Concurrent Soft Tissue Chondroma and Periosteal Chondroma of Thumb. Eur J Gen Med 2009; 6: 257-61.
Bell WC, Klein MJ, Pitt MJ, Siegal GP. Molecular pathology of chondroid neoplasms: Part 1, benign lesions. Skeletal Radiol 2006; 35: 805-13.
Dahlin DC, Salvador AH. Cartilaginous tumors of the soft tissues of the hands and feet. Mayo Clin Proc 1974;49: 721-6.
Faraj A. A Soft tissue chondroma in a finger: a case report. Acta Orthopaedica Belgica, 2002;68:3.
Dahlin DC, Salvador AH. Cartilaginous tumors of the soft tissues of the hands and feet. Mayo Clin Proc 1974;49: 721-726.
Ekanem, Victor J, Adeoye II, Marchie TT. Recurrent extra skeletal soft tissue chondroma in a black african female: report of a case and review of literature. J Med Biomed Res.; 2006;5:18-21.
Bansal M, Goldman AB, DiCarlo EF, McCormack R. Soft tissue chondromas: diagnosis and differential diagnosis. Skeletal Radiol 1993;22: 309-15
Zlatkin MB, Lander PH, Begin LR, Hadjipavlou A. Soft-tissue chondromas. AJR Am J Roentgenol 1985;144: 1263-7.
Goyal P, Sehgal S, Ghosh S, Mittal D, Singh S. Extraskeletal Chondroma of Anterior Abdominal Wall in a Child. APSP Journal of Case Reports. 2013;4(3):54.
Legeai-Mallet L, Margaritte-Jeannin P, Lemdani M, Le Merrer M, Plauchu H, Maroteaux P, et al. An extension of the admixture test for the study of genetic heterogeneity in hereditary multiple exostoses. Hum Genet 1997; 99: 298-302
Reith JD, Bauer TW, Joyce MJ. Paraarticular osteochondroma of the knee: report of 2 cases and review of the literature. Clin Orthop 1997; 225-32.
Weiss SW, Goldblum JR. Cartilagineous soft tissue tumors. In: Enzinger and Weiss's Soft Tissue Tumours. 4th ed. Mosby-Harcourt: Philadelphia 2001; pp. 1361-1388.
Isayama T, Iwasaki H, Kikuchi M. Chondroblastomalike extraskeletal chondroma. Clin Orthop 1991;214-217.
Thool AA, Raut WK, Lele VR, Bobhate SK. Fine needle aspiration cytology of soft tissue chondroma. A case report. Acta Cytol. 2001;45(1):86-8.
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