Histomorphological Analysis of Lesions In Nephrectomy Specimens: A 4 Years Study In A Rural Hospital In India- Our Experience.

  • Rajshri P Damle
  • N V Dravid
  • Ashish Patil Rawandale
  • Akshay Surana
Keywords: Chronic nonspecific pyelonephritis, end stage renal disease, nephrectomy


Background- Kidney is involved in various pathological conditions ranging from non-neoplastic lesions to neoplastic diseases like renal cell carcinoma. Nephrectomy remains the treatment of choice for patient care in end stage renal diseases from various causes and neoplastic lesions.Objective: To study the histomorphological spectrum and frequency of various lesions in nephrectomy specimens.Material and methods:- A observational retrospective research study included 33 nephrectomy specimens in the department of pathology over a period of 4 years (April 2012 to April 2016).Clinical details and radiological findings were noted from records and clinico-histomorphological correlation was done.Results: - A total of 33 nephrectomy specimens were studied. Age distribution varied from 16 to 71 years with male to female ratio of 2:1.Benign lesions comprised of maximum cases (75.76%) while malignant lesion were present in 24.24% cases. Chronic nonspecific pyelonephritis was the predominant non-neoplastic finding followed by xanthogranulomatous pyelonephritis. Renal cell carcinoma was the most common malignant lesion in this study.Conclusion: Chronic nonspecific pyelonephritis leading to end stage renal disease is the commonest causative factor in our region ; may be due to consumption of hard water in rural areas.DOI: 10.21276/APALM.1111

Author Biography

Department Of PathologyAssociate Professor


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Original Article